Sardomozide

Research use only, not for human use.

Sardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).

Sardomozide is an inhibitor of S-adenosylmethionine decarboxylase (SAMDC, IC50 = 5 nM).(In Vitro):In CHO/664 cells treated with DENSPM, Sardomozide inhibits cell growth without vacuole formation. Sardomozide (3 μM) reduces intracellular SAMDC activity to 10%.

Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells.

——

CGP 48664 dihydrochloride

Others

Other Targets

Platelet aggregation

——

——

138794-73-7

303.19

C11H16Cl2N6

>98% (HPLC)

In Vitro:?DMSO : 10 mg/mL (32.98 mM)

N=C(C1=CC=CC2=C1CCC2=NNC(N)=N)N.[H]Cl.[H]Cl

——

(-20℃)

With Ice Pack

≥ 2 years