Cart
sales@molnova.com
DHODH-IN-16
CAS No. 2511248-11-4
DHODH-IN-16( —— )
Catalog No. M28280 CAS No. 2511248-11-4
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 180 | In Stock |
|
| 5MG | 163 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDHODH-IN-16
-
NoteResearch use only, not for human use.
-
Brief DescriptionDHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
-
DescriptionDHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).(In Vitro):DHODH-IN-16 inhibited the growth of MOLM-13 cells effectively (IC50 = 0.2 nM) .
-
In VitroDHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM.
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
RecptorTNF-α
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2511248-11-4
-
Formula Weight436.48
-
Molecular FormulaC24H25FN4O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (229.11 mM)
-
SMILESCCN(C(CO)=NN1c(cc(C(C(C)C)=CN(c2c(C)cccc2)C2=O)c2c2)c2F)C1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.
molnova catalog
related products
-
hDHODH-IN-3
hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.
-
DHODH-IN-1
DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM.
-
AG-636
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.
