Inaxaplin

CAS No. 2446816-88-0

Inaxaplin( VX-147 )

Catalog No. M28276 CAS No. 2446816-88-0

Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 167 In Stock
5MG 150 In Stock
10MG 236 In Stock
25MG 377 In Stock
50MG 529 In Stock
100MG 731 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Inaxaplin
  • Note
    Research use only, not for human use.
  • Brief Description
    Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.
  • Description
    Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease.(In Vitro):Inaxaplin is an apolipoprotein L1 function inhibitor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VX-147
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    14-3-3 protein-protein interaction
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2446816-88-0
  • Formula Weight
    417.38
  • Molecular Formula
    C21H18F3N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (119.79 mM)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mancini M, et al. A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinib. J Pharmacol Exp Ther. 2011 Mar;336(3):596-604.
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