Pomalidomide-PEG4-C2-NH2 hydrochloride( —— )

Catalog No. M28272 CAS No. 2357105-92-9

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Pomalidomide-PEG4-C2-NH2 hydrochloride
Note

Research use only, not for human use.
Brief Description

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
Description

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

SOS1
Research Area

——
Indication

——

Chemical Information

CAS Number

2357105-92-9
Formula Weight

528.98
Molecular Formula

C23H33ClN4O8
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 220 mg/mL (415.89 mM)
SMILES

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.[H]Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ketcham JM, et al. Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction. J Med Chem. 2022 Jul 28;65(14):9678-9690.

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