TLR7/8/9-IN-1

CAS No. 2180127-82-4

TLR7/8/9-IN-1( —— )

Catalog No. M28232 CAS No. 2180127-82-4

TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 169 In Stock
2MG 64 In Stock
5MG 113 In Stock
10MG 188 In Stock
25MG 307 In Stock
50MG 439 In Stock
100MG 597 In Stock
200MG 853 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TLR7/8/9-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
  • Description
    TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    5-LOX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2180127-82-4
  • Formula Weight
    435.6
  • Molecular Formula
    C27H37N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 83.33 mg/mL (191.30 mM)
  • SMILES
    CC(C)c1c(-c(cc2)cc(OC)c2OC)[nH]c2c1cc(C1CCN(CCNC)CC1)cc2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Matthew Hutzler J, et al. In vitro-in vivo correlation and translation to the clinical outcome for CJ-13,610, a novel inhibitor of 5-lipoxygenase. Drug Metab Dispos. 2010 Jul;38(7):1113-21.
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