Afimetoran

CAS No. 2171019-55-7

Afimetoran( BMS-986256 )

Catalog No. M28229 CAS No. 2171019-55-7

Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 215 In Stock
5MG 187 In Stock
10MG 312 In Stock
25MG 530 In Stock
50MG 733 In Stock
100MG 1042 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Afimetoran
  • Note
    Research use only, not for human use.
  • Brief Description
    Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
  • Description
    Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    BMS-986256
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    mitotic kinesin Kif18A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2171019-55-7
  • Formula Weight
    444.57
  • Molecular Formula
    C26H32N6O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (224.94 mM)
  • SMILES
    CC(C)c1c(-c2cn3ncnc3c(C)c2C)[nH]c2c1cc(C1CCN(CC(N)=O)CC1)cc2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tamayo NA, et al. Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe. J Med Chem. 2022;65(6):4972-4990.
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