Cart
sales@molnova.com
Cevidoplenib dimesylate
CAS No. 2043659-93-2
Cevidoplenib dimesylate( —— )
Catalog No. M28223 CAS No. 2043659-93-2
Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 186 | In Stock |
|
| 5MG | 136 | In Stock |
|
| 10MG | 188 | In Stock |
|
| 25MG | 373 | In Stock |
|
| 50MG | 548 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCevidoplenib dimesylate
-
NoteResearch use only, not for human use.
-
Brief DescriptionCevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.
-
DescriptionCevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.(In Vitro):Cevidoplenib dimesylate inhibits the activity of SYK through binding to SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells, and B cells.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetSyk
-
RecptorHSF1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2043659-93-2
-
Formula Weight665.74
-
Molecular FormulaC27H35N7O9S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (37.55 mM)
-
SMILESCC1=NN(C2=NC(NC3=CC4=C(N(C)C=C4C(C5CC5)=O)C=C3)=NC=C2)C=C1CN6C[C@H](O)CO6.CS(=O)(O)=O.CS(=O)(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.
molnova catalog
related products
-
Sovleplenib
Sovleplenib (HMPL523) is an orally available, selective and potent inhibitor of the splenic tyrosine kinase SYK with an IC50 of 25 nM.Sovleplenib has antitumor activity and may be used in studies of immune thrombocytopenia (ITP).
-
Cevidoplenib dimesyl...
Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.
-
BAY 61-3606 dihydroc...
A potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM.
