Cevidoplenib dimesylate( —— )

Catalog No. M28223 CAS No. 2043659-93-2

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HNMR

HPLC

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Product Name

Cevidoplenib dimesylate
Note

Research use only, not for human use.
Brief Description

Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.
Description

Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.(In Vitro):Cevidoplenib dimesylate inhibits the activity of SYK through binding to SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells, and B cells.
In Vitro

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In Vivo

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Synonyms

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Pathway

Angiogenesis
Target

Syk
Recptor

HSF1
Research Area

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Indication

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CAS Number

2043659-93-2
Formula Weight

665.74
Molecular Formula

C27H35N7O9S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (37.55 mM)
SMILES

CC1=NN(C2=NC(NC3=CC4=C(N(C)C=C4C(C5CC5)=O)C=C3)=NC=C2)C=C1CN6C[C@H](O)CO6.CS(=O)(O)=O.CS(=O)(O)=O
Chemical Name

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1.Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.

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