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Cyfluthrin

CAS No. 68359-37-5

Cyfluthrin( —— )

Catalog No. M28140 CAS No. 68359-37-5

Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cyfluthrin
  • Note
    Research use only, not for human use.
  • Brief Description
    Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.
  • Description
    Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests.(In Vitro):Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. Cyfluthrin increased significantly gene expressions of apoptosis, proinflammation and oxidative stress (Bax, Bcl-2, Casp-3, BNIP3, AKT1, p53, APAF1, NFκB1, TNFα and Nrf2) mediators. In the most genes, the mRNA levels induced by cyfluthrin were partially reduced by MEL (1 μM).
  • In Vitro
    Cyfluthrin (0-50 μM; 24 hours) is against SH-SY5Y cell growth with an IC50 and an IC30 of 19.39 μM and 4.81 μM, respectively.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    HIV-1 reverse transcriptase|Antiviral
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    68359-37-5
  • Formula Weight
    434.29
  • Molecular Formula
    C22H18Cl2FNO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c1ccc(F)c(Oc2ccccc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Singh IR, et al. Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome. PLoS One. 2010 Apr 1;5(4):e9948.
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