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T2AA

CAS No. 1380782-27-3

T2AA( 4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol | ZINC95605533 )

Catalog No. M28054 CAS No. 1380782-27-3

T2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 55 In Stock
5MG 50 In Stock
10MG 81 In Stock
25MG 169 In Stock
50MG 272 In Stock
100MG 397 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    T2AA
  • Note
    Research use only, not for human use.
  • Brief Description
    T2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction.
  • Description
    T2AA is an inhibitor of proliferating cell nuclear antigen (PCNA) with IC50 of 1 μM for PCNA/PIP-box peptide interaction. T2AA suppresses cancer cell growth and causes DNA replication stress by stalling DNA replication forks and inhibiting PCNA interaction with DNA polymerase δ.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    4-[4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy]phenol | ZINC95605533
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    Antifungal|Coagulation factor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1380782-27-3
  • Formula Weight
    511.09
  • Molecular Formula
    C15H15I2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (195.66 mM)
  • SMILES
    O(C1=C(I)C=C(C[C@@H](CO)N)C=C1I)C2=CC=C(O)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kumar N, et al. Isolation and antifungal properties of cyclo(D-Tyr-L-Leu) diketopiperazine isolated from Bacillus sp. associated with rhabditid entomopathogenic nematode. Natural Product Research 2013, 27(23):2168-217
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