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SHP099

CAS No. 1801747-42-1

SHP099( SHP099 free base | SHP099 | SHP-099 | SHP 099 )

Catalog No. M28048 CAS No. 1801747-42-1

SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 52 In Stock
2MG 42 In Stock
5MG 68 In Stock
10MG 96 In Stock
25MG 168 In Stock
50MG 220 In Stock
100MG 401 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    SHP099
  • Note
    Research use only, not for human use.
  • Brief Description
    SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
  • Description
    SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SHP099 free base | SHP099 | SHP-099 | SHP 099
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1801747-42-1
  • Formula Weight
    352.26
  • Molecular Formula
    C16H19Cl2N5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 12 mg/mL (34.07 mM)
  • SMILES
    CC1(N)CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Smith JL, et al. Fusarium graminearum Mycotoxins in Maize Associated With Striacosta albicosta (Lepidoptera: Noctuidae) Injury. J Econ Entomol. 2018 Mar 14.
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