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VU0360172
CAS No. 1310012-12-4
VU0360172( VU-0360172 | VU 0360172 )
Catalog No. M27938 CAS No. 1310012-12-4
VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 160 | Get Quote |
|
| 10MG | 260 | Get Quote |
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| 25MG | 533 | Get Quote |
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| 50MG | 768 | Get Quote |
|
| 100MG | 1062 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameVU0360172
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NoteResearch use only, not for human use.
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Brief DescriptionVU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).
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DescriptionVU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).(In Vivo):VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice.
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In Vitro——
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In Vivo——
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SynonymsVU-0360172 | VU 0360172
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PathwayNeuroscience
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TargetGluR
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RecptorCK1
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Research Area——
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Indication——
Chemical Information
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CAS Number1310012-12-4
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Formula Weight294.329
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Molecular FormulaC18H15FN2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (283.13 mM)
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SMILESFc1cccc(c1)C#Cc1ccc(cn1)C(=O)NC1CCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ana MARTíNEZ GIL, et al. Preparation of substituted benzothiazoles as casein kinase 1 inhibitors for the treatment of human diseases. WO2014114825A1
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