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VPC-13163
CAS No. 6637-10-1
VPC-13163( VPC 13163 | VPC13163 | NSC 52361 | NSC52361 | NSC52361 | 2,3-dihydro-2,3'-Bi-1H-indole )
Catalog No. M27934 CAS No. 6637-10-1
VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 168 | In Stock |
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| 5MG | 302 | In Stock |
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| 10MG | 447 | In Stock |
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| 25MG | 714 | In Stock |
|
| 50MG | 1017 | In Stock |
|
| 100MG | 1368 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2673 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVPC-13163
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NoteResearch use only, not for human use.
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Brief DescriptionVPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line.
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DescriptionVPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
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In Vitro——
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In Vivo——
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SynonymsVPC 13163 | VPC13163 | NSC 52361 | NSC52361 | NSC52361 | 2,3-dihydro-2,3'-Bi-1H-indole
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PathwayOthers
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TargetOther Targets
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RecptorCCK
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Research Area——
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Indication——
Chemical Information
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CAS Number6637-10-1
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Formula Weight234.302
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Molecular FormulaC16H14N2
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Purity>98% (HPLC)
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Solubility——
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SMILESC1C(Nc2ccccc12)c1c[nH]c2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Eric Lattmann, et al. A preparation of novel ureido - and amido-?pyrazolone derivatives, useful as CCK receptor ligands and CCK antagonists. WO2004106306A1
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