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Biotin-ONP
CAS No. 33755-53-2
Biotin-ONP( (+)-Biotin 4-nitrophenyl ester )
Catalog No. M27001 CAS No. 33755-53-2
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | 27 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBiotin-ONP
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NoteResearch use only, not for human use.
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Brief Description(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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Description(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms(+)-Biotin 4-nitrophenyl ester
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PathwayOthers
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TargetOther Targets
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RecptorHDAC1
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Research Area——
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Indication——
Chemical Information
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CAS Number33755-53-2
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Formula Weight365.4
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Molecular FormulaC16H19N3O5S
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)Oc3ccc(cc3)[N+]([O-])=O)[C@@]1([H])NC(=O)N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Patnaik D, et al. Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration. ACS Chem Neurosci. 2021 Jan 20;12(2):271-284.
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