Cart
sales@molnova.com
CJ-13,610 hydrochloride
CAS No. 179420-27-0
CJ-13,610 hydrochloride( —— )
Catalog No. M27863 CAS No. 179420-27-0
CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 151 | In Stock |
|
| 5MG | 93 | In Stock |
|
| 10MG | 161 | In Stock |
|
| 25MG | 354 | In Stock |
|
| 50MG | 517 | In Stock |
|
| 100MG | 728 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1535 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCJ-13,610 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionCJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.
-
DescriptionCJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.(In Vitro):In intact human polymorphonuclear leukocytes (PMNL), challenged with the Ca(2+)-ionophore A23187, CJ-13,610 hydrochloride potently suppressed 5-LOX product formation with an IC50 of 70 nM. In transfected HeLa cells, CJ-13,610 hydrochloride only slightly discriminated between phosphorylatable wild-type 5-LOX and a 5-LOX mutant that lacks phosphorylation sites.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetLipoxygenase
-
RecptorSTAT3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number179420-27-0
-
Formula Weight429.96
-
Molecular FormulaC22H24ClN3O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.O=C(N)C1(C=2C=CC=C(SC3=CC=C(C=C3)N4C=CN=C4C)C2)CCOCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ayyiliath M Sajith, et al. Pyrimidine-2,4-dione targets STAT3 signaling pathway to induce cytotoxicity in hepatocellular carcinoma cells. Bioorg Med Chem Lett. 2021 Oct 15;50:128332.
molnova catalog
related products
-
Montelukast
Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.
-
marmesin
Marmesin is a coumarin originally isolated from the mature bark of A. marmelosexhibiting COX-2/5-LOX dual inhibitory activity.
-
LOX-IN-3 dihydrochlo...
LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50<10 μM) and human LOXL2 (IC50<1 μM)activities.
