EUK 134

CAS No. 81065-76-1

EUK 134( EUK-134 | EUK-134 | EUK-134 )

Catalog No. M19135 CAS No. 81065-76-1

EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 29 In Stock
25MG 58 In Stock
50MG 99 In Stock
100MG 152 In Stock
200MG Get Quote In Stock
500MG 369 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    EUK 134
  • Note
    Research use only, not for human use.
  • Brief Description
    EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
  • Description
    EUK-134 is an antioxidant compound with superoxide dismutase and catalase activity for oxidative species such as peroxynitrite, superoxide, and hydrogen peroxide.
  • In Vitro
    Cell Viability Assay Cell Line:NRK-52E cells Concentration:0, 1, 3, 10, 30, 100, and 300 μM Incubation Time:24 hours Result:Co-incubation with Paraquat (1 mM) and increasing concentrations of EUK-134 (1-300 μM) resulted in a significant reduction in paraquat-induced cellular injury and death at 100 and 300 μM.
  • In Vivo
    ——
  • Synonyms
    EUK-134 | EUK-134 | EUK-134
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    81065-76-1
  • Formula Weight
    416.74
  • Molecular Formula
    C18H18ClMnN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 10 mg/mL (24.00 mM)
  • SMILES
    COC1=C2O[Mn]34(Cl)OC5=C(OC)C=CC=C5C=[N]3CC[N]4=CC2=CC=C1
  • Chemical Name
    chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]]]-manganese

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Baker K, et al. J Pharmacol Exp Ther. 1998, 284(1), 215-221.
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