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EUK 134
CAS No. 81065-76-1
EUK 134( EUK-134 | EUK-134 | EUK-134 )
Catalog No. M19135 CAS No. 81065-76-1
EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 29 | In Stock |
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| 25MG | 58 | In Stock |
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| 50MG | 99 | In Stock |
|
| 100MG | 152 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 369 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEUK 134
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NoteResearch use only, not for human use.
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Brief DescriptionEUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
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DescriptionEUK-134 is an antioxidant compound with superoxide dismutase and catalase activity for oxidative species such as peroxynitrite, superoxide, and hydrogen peroxide.
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In VitroCell Viability Assay Cell Line:NRK-52E cells Concentration:0, 1, 3, 10, 30, 100, and 300 μM Incubation Time:24 hours Result:Co-incubation with Paraquat (1 mM) and increasing concentrations of EUK-134 (1-300 μM) resulted in a significant reduction in paraquat-induced cellular injury and death at 100 and 300 μM.
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In Vivo——
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SynonymsEUK-134 | EUK-134 | EUK-134
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PathwayImmunology/Inflammation
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TargetLipoxygenase
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RecptorAβ
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number81065-76-1
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Formula Weight416.74
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Molecular FormulaC18H18ClMnN2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 10 mg/mL (24.00 mM)
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SMILESCOC1=C2O[Mn]34(Cl)OC5=C(OC)C=CC=C5C=[N]3CC[N]4=CC2=CC=C1
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Chemical Namechloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]]]-manganese
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Baker K, et al. J Pharmacol Exp Ther. 1998, 284(1), 215-221.
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