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BZAD01
CAS No. 305339-41-7
BZAD01( BZAD-01 | BZAD 01 )
Catalog No. M27808 CAS No. 305339-41-7
BZAD01 is a selective NMDA NR1A/2B receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | Get Quote |
|
| 10MG | 335 | Get Quote |
|
| 25MG | 566 | Get Quote |
|
| 50MG | 806 | Get Quote |
|
| 100MG | 1098 | Get Quote |
|
| 500MG | 2205 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBZAD01
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NoteResearch use only, not for human use.
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Brief DescriptionBZAD01 is a selective NMDA NR1A/2B receptor antagonist.
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DescriptionBZAD01 is a selective NMDA NR1A/2B receptor antagonist.(In Vivo):Parkinsonism was induced by microinjection of the toxin, 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle (MFB) of 40 Sprague-Dawley rats. Parkinsonism and the efficacy of drugs were assessed using a battery of behavioural tests including balance beam, apomorphine-induced rotation, body axis bias or "curling", head position bias and disengage sensorimotor latency test. The main effects were that BZAD01 co-administration prevented chronic levodopa-induced potentiation of apomorphine rotation. However levodopa-treated rats were slower than either controls or BZAD-01-treated rats in the locomotor test.
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In Vitro——
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In Vivo——
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SynonymsBZAD-01 | BZAD 01
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PathwayMembrane Transporter/Ion Channel
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TargetNMDAR
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RecptorGuanylate cyclase
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Research Area——
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Indication——
Chemical Information
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CAS Number305339-41-7
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Formula Weight362.275
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Molecular FormulaC16H12F6N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Methanol : 250 mg/mL (690.09 )
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SMILESFC(F)(F)Oc1ccc(cc1)C(=N)NCc1ccccc1C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Barbara ALBRECHT-KüPPER, et al. Selective partial adenosine a1 receptor agonists in combination with soluble guanylyl cyclase (sgc) stimulators and/or activators. WO2018153899A1.
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