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VU-1545
CAS No. 890764-63-3
VU-1545( VU 1545 )
Catalog No. M27735 CAS No. 890764-63-3
VU 1545 is mGlu5 positive allosteric modulator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | In Stock |
|
| 5MG | 79 | In Stock |
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| 10MG | 126 | In Stock |
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| 25MG | 244 | In Stock |
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| 50MG | 369 | In Stock |
|
| 100MG | 532 | In Stock |
|
| 200MG | 714 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVU-1545
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NoteResearch use only, not for human use.
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Brief DescriptionVU 1545 is mGlu5 positive allosteric modulator.
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DescriptionVU 1545 is mGlu5 positive allosteric modulator.
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In VitroVU-1545 (10 and 100 μM) promotes AKT activation. VU-1545 at the concentrations of 0.1 and 1.0 μM efficiently promots Akt activation above basal levels Western Blot Analysis Cell Line:Neuronal cells Concentration:10 and 100 μM Incubation Time:5 minutes Result:Promoted Akt phosphorylation as efficiently at the concentration of 10.0 μM as at the concentration of 100.0 μM.
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In Vivo——
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SynonymsVU 1545
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PathwayNeuroscience
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TargetGluR
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RecptorMicrobial Metabolite|TGR5|FXR
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Research Area——
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Indication——
Chemical Information
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CAS Number890764-63-3
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Formula Weight402.385
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Molecular FormulaC22H15FN4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (248.52 mM)
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SMILES[O-][N+](=O)c1ccc(cc1)C(=O)Nc1cc(nn1-c1ccccc1F)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jones H, Alpini G, Francis H. Bile acid signaling and biliary functions. Acta Pharm Sin B. 2015 Mar;5(2):123-8.
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