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VU-1545

CAS No. 890764-63-3

VU-1545( VU 1545 )

Catalog No. M27735 CAS No. 890764-63-3

VU 1545 is mGlu5 positive allosteric modulator.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	209	Get Quote
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100MG	972	Get Quote
500MG	1944	Get Quote
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Biological Information

Product Name

VU-1545
Note

Research use only, not for human use.
Brief Description

VU 1545 is mGlu5 positive allosteric modulator.
Description

VU 1545 is mGlu5 positive allosteric modulator.
In Vitro

VU-1545 (10 and 100 μM) promotes AKT activation. VU-1545 at the concentrations of 0.1 and 1.0 μM efficiently promots Akt activation above basal levels Western Blot Analysis Cell Line:Neuronal cells Concentration:10 and 100 μM Incubation Time:5 minutes Result:Promoted Akt phosphorylation as efficiently at the concentration of 10.0 μM as at the concentration of 100.0 μM.
In Vivo

——
Synonyms

VU 1545
Pathway

Neuroscience
Target

GluR
Recptor

Microbial Metabolite|TGR5|FXR
Research Area

——
Indication

——

Chemical Information

CAS Number

890764-63-3
Formula Weight

402.385
Molecular Formula

C22H15FN4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (248.52 mM)
SMILES

[O-][N+](=O)c1ccc(cc1)C(=O)Nc1cc(nn1-c1ccccc1F)-c1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jones H, Alpini G, Francis H. Bile acid signaling and biliary functions. Acta Pharm Sin B. 2015 Mar;5(2):123-8.

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