Cart
sales@molnova.com
Home - Products - Others - Other Targets - TCS PrP Inhibitor 13

TCS PrP Inhibitor 13

CAS No. 34320-83-7

TCS PrP Inhibitor 13( 5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One )

Catalog No. M27727 CAS No. 34320-83-7

TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 32 In Stock
5MG 30 In Stock
10MG 50 In Stock
25MG 102 In Stock
50MG 155 In Stock
100MG 239 In Stock
200MG 340 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    TCS PrP Inhibitor 13
  • Note
    Research use only, not for human use.
  • Brief Description
    TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.
  • Description
    TCS PrP Inhibitor 13 is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.(In Vitro):In Schwannoma cells, administration of 0-500 μM TCS PrP Inhibitor 13 reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and increases expression of cleaved caspase-3 significantly. TCS PrP Inhibitor 13 also significantly reduces the number of proliferating, Ki67-positive cells and total cell number in Schwannoma cells.
  • In Vitro
    TCS PrP Inhibitor 13 (0~500 μM; Schwannoma cells) significantly reduces levels of total ERK1/2, pAKT, total FAK, Cyclin D1, PrPC and significantly increases expression of cleaved caspase-3. TCS PrP Inhibitor 13 (Schwannoma cells) significantly reduces the number of proliferating, Ki67-positive cells and total cell number.
  • In Vivo
    ——
  • Synonyms
    5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34320-83-7
  • Formula Weight
    281.271
  • Molecular Formula
    C15H11N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (355.53 mM)
  • SMILES
    [O-][N+](=O)c1ccc(cc1)C1=NN(C(=O)C1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ensslin HK, Kovar KA, Maurer HH. Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay. J Chromatogr B Biomed Appl. 1996 Aug 30;683(2):189-97.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Lacutamab

    Lacutamab (IPH 4102) is a potent and selective humanized anti-KIR3DL2 antibody.Lacutamab has potential anticancer activity for the study of leukemia and lymphoma.

  • Defensin HNP-3 (huma...

    Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors.

  • DpC

    DPC is an antitumor compound that inhibits cancer cell proliferation with an IC50 of 0.007-0.096 μM.DPC is involved in a variety of anticancer therapies and can be used in cancer research.

Sign In Join Free