Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Hedgehog (Hh) - SMANT hydrochloride

SMANT hydrochloride

CAS No. 1177600-74-6

SMANT hydrochloride( N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride | N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamide hydrochloride | N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide | hydrochloride | SMANT HCl )

Catalog No. M27712 CAS No. 1177600-74-6

SMANT hydrochloride is an antagonist of Smoothened accumulation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 50 Get Quote
10MG 80 Get Quote
25MG 160 Get Quote
50MG 282 Get Quote
100MG 483 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    SMANT hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    SMANT hydrochloride is an antagonist of Smoothened accumulation.
  • Description
    SMANT hydrochloride is an antagonist of Smoothened accumulation.
  • In Vitro
    SMANT (0-10 μM, NIH/3T3 cells) hydrochloride inhibits Hh induced Smo accumulation at the primary cilium (IC50: 1.1 μM).SMANT (0-10 μM, NIH/3T3 cells) hydrochloride inhibits Smo and SmoM2 activity, and blocks the stimulatory action of SAG in Gli-luciferase assay.SMANT (0-10 μM) hydrochloride inhibits proliferation of cerebellar granule-cell neural progenitors (CGNP) (isolated from Ptch1+/? neonates) induced by Shh.
  • In Vivo
    ——
  • Synonyms
    N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride | N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamide hydrochloride | N-(4-bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide | hydrochloride | SMANT HCl
  • Pathway
    GPCR/G Protein
  • Target
    Hedgehog (Hh)
  • Recptor
    5-HT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1177600-74-6
  • Formula Weight
    375.73
  • Molecular Formula
    C16H24BrClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 83.33 mg/mL (221.78 mM)
  • SMILES
    Cl.CC1CC(C)CN(CCC(=O)Nc2ccc(Br)cc2)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Torrisi SA, et al. Buspirone Counteracts MK-801-Induced Schizophrenia-Like Phenotypes through Dopamine D(3) Receptor Blockade. Front Pharmacol. 2017 Oct 4;8:710.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • RUSKI-201

    A potent, selective and cell active Hedgehog acyltransferase (Hhat) inhibitor with IC50 of 0.87 uM.

  • Cyclopamine

    A natural steroidal alkaloid that inhibits hedgehog (Hh) signaling with IC50 of 46 nM.

  • Naftifine hydrochlor...

    Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity.

Sign In Join Free