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ALLO-2
CAS No. 1357350-60-7
ALLO-2( —— )
Catalog No. M22837 CAS No. 1357350-60-7
ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 150 | In Stock |
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| 5MG | 136 | In Stock |
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| 10MG | 212 | In Stock |
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| 25MG | 352 | In Stock |
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| 50MG | 490 | In Stock |
|
| 100MG | 644 | In Stock |
|
| 200MG | 886 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameALLO-2
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NoteResearch use only, not for human use.
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Brief DescriptionALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
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DescriptionALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetHedgehog (Hh)
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RecptorSmoothened
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Research Area——
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Indication——
Chemical Information
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CAS Number1357350-60-7
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Formula Weight371.32
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Molecular FormulaC18H12F3N5O
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (336.64 mM; Need ultrasonic)
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SMILESFC(F)(OC1=CC=C(C=C1)C2=NC(NC3=CC4=C(C=C3)NN=C4)=NC=C2)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tao H, et al. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. Chem Biol. 2011 Apr 22;18(4):432-7.
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