SCS

Research use only, not for human use.

SCS a potent selective inhibitor of α2β1γ1θ GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC50 of 32 nM.

SCS a potent selective inhibitor of α2β1γ1θ GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC50 of 32 nM.

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Animal Model:BALB/c mice; tonic, phasic and Capsaicin (HY-10448) nociception modelDosage:10, 25, 50, and 75 mg/kg Administration:IP, single dose Result:Produced a significant protection on tonic, phasic and capsaicin nociception in a dose-dependent manner.Animal Model:BALB/c mice, Oxaliplatin (HY-17371)-induced neuropathic nociception model Dosage:50 and 75 mg/kg Administration:IP, single dose Result:Significantly attenuated the paw withdrawal threshold changes associated with Oxaliplatin. Significantly increased the percent antinociception during 30-120 min.

Salicylidene salicylhydrazide

Others

Other Targets

Histamine Receptor|Autophagy|Apoptosis

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3232-36-8

256.261

C14H12N2O3

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (195.11 mM)

Oc1ccccc1C(=O)NN\C=C1\C=CC=CC1=O

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(-20℃)

With Ice Pack

≥ 2 years