3,5-Dinitrocatechol

Research use only, not for human use.

OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.

OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.(In Vitro):OR-486 is highly effective (IC50 = 12 nM) and selective in inhibiting COMT activity in vitro.(In Vivo):In mouse trachea (β1-AR dominant), significant suppression of ISO-induced relaxation was observed with the addition of OR-486. In GP trachea, in the presence of clorgiline plus OR-486, both normetadrenaline (NMA) and metadrenaline (MA) (10-4 M) significantly suppressed ISO-induced relaxation.

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OR-486 | 3,5-Dinitropyrocatechol

Metabolic Enzyme/Protease

Transferase

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7659-29-2

200.106

C6H4N2O6

>98% (HPLC)

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Oc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O

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(-20℃)

With Ice Pack

≥ 2 years