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Home - Products - Metabolic Enzyme/Protease - Retinoid Receptor - MM 11253

MM 11253

CAS No. 345952-44-5

MM 11253( MM-11253 )

Catalog No. M27662 CAS No. 345952-44-5

MM 11253 is a RARγ antagonist with IC50 of 44nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MM 11253
  • Note
    Research use only, not for human use.
  • Brief Description
    MM 11253 is a RARγ antagonist with IC50 of 44nM.
  • Description
    MM 11253 is a RARγ antagonist with IC50 of 44nM.(In Vitro):MM11253 blocks the ability of MM11254 and MM11389 to inhibit squamous cell carcinoma cell growth .
  • In Vitro
    MM11253 blocks the ability of MM11254 and MM11389 to inhibit squamous cell carcinoma cell growth.
  • In Vivo
    ——
  • Synonyms
    MM-11253
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Retinoid Receptor
  • Recptor
    AMPK α2β2γ1|AMPK α1β1γ1|AMPK α2β1γ1|AMPK α1β2γ1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    345952-44-5
  • Formula Weight
    462.67
  • Molecular Formula
    C28H30O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (270.17 mM)
  • SMILES
    CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc2cc(ccc2c1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang LN, et al. Novel small-molecule AMP-activated protein kinase allosteric activator with beneficial effects in db/db mice. PLoS One. 2013 Aug 20;8(8):e72092.
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