ICI 89406

CAS No. 53671-71-9

ICI 89406( 1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea )

Catalog No. M27638 CAS No. 53671-71-9

ICI 89406 is a β-adrenergic antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 148 In Stock
5MG 141 In Stock
10MG 201 In Stock
25MG 378 In Stock
50MG 542 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ICI 89406
  • Note
    Research use only, not for human use.
  • Brief Description
    ICI 89406 is a β-adrenergic antagonist.
  • Description
    ICI 89406 is a β-adrenergic antagonist.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Rats.Dosage:0.6, 5 or 50 mg/kg.Administration:Orally (5 or 50 mg/kg), i.p. (5 mg/kg), i.v. 0.6 (0.6 mg/kg) (Pharmacokinetic Analysis).Result:Following oral administration, the dose of 5 mg/kg urinary and faecal excretion accounted for 5.8 + 0.7% and 96.4 + 2.1%. The dose of 50 mg/kg urinary and faecal excretion accounted for 14.0 + 4.0% and 78.4 + 2.4%. The proportions of unchanged drug and metabolites in urine were independent of the dose. The unchanged drug accounted for 81.6% of the faecal components after a dose of 5 mg/kg but this was reduced to 47.8%.
  • Synonyms
    1-[2-[[3-(2-cyanophenoxy)-2-hydroxypropyl]amino]ethyl]-3-phenylurea
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    CaSR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    53671-71-9
  • Formula Weight
    354.41
  • Molecular Formula
    C19H22N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@@H](CNCCNC(=O)Nc1ccccc1)COc1ccccc1C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Altunta? EE, et al. The effects of mometasone furoate and strontium chloride in a rat model of allergic rhinitis. Ear Nose Throat J. 2018 Jan-Feb;97(1-2):E1-E7.
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