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Clenbuterol hydrochloride?

CAS No. 21898-19-1

Clenbuterol hydrochloride?( NAB 365 )

Catalog No. M13495 CAS No. 21898-19-1

Clenbuterol hydrochloride is a β2 adrenergic receptor agonist. It is a powerful bronchodilator withfat burning properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Clenbuterol hydrochloride?
  • Note
    Research use only, not for human use.
  • Brief Description
    Clenbuterol hydrochloride is a β2 adrenergic receptor agonist. It is a powerful bronchodilator withfat burning properties.
  • Description
    Clenbuterol hydrochloride is a β2 adrenergic receptor agonist. It is a powerful bronchodilator withfat burning properties.
  • In Vitro
    Clenbuterol increases lipolysis in rat primary adipocytes compared with control. Free glycerol release into the culture medium is 158% and 190% of control values in cultures containing 0.1, or 1 μM Clenbuterol, respectively.
  • In Vivo
    Clenbuterol (0.01-0.5 mg/kg; i.p.; male Long-Evans rats) hydrochloride reduces the cortical infarct volume in Long-Evans rats as measured 7 days after permanent occlusion of the middle cerebral artery.
  • Synonyms
    NAB 365
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21898-19-1
  • Formula Weight
    313.65
  • Molecular Formula
    C12H19Cl3N2O
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    OC(CNC(C)(C)C)C1=CC(Cl)=C(N)C(Cl)=C1.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim HK, et al. Effect of clenbuterol on apoptosis, adipogenesis, and lipolysis in adipocytes.J PhysiolBiochem. 2010 Sep;66(3):197-203. 2. Hoshino D, et al. Clenbuterol, a β2-adrenergic agonist, reciprocally alters PGC-1 alpha and RIP140 and reduces fatty acid and pyruvate oxidation in rat skeletal muscle.Am J PhysiolRegulIntegr Comp Physiol. 2012 Feb 1;302(3):R373-84. 3. O'Donnell JM, et al. Effects of clenbuterol and antidepressant drugs on beta adrenergic receptor/N-protein coupling in the cerebral cortex of the rat.J PharmacolExpTher. 1985 Jul;234(1):30-6. 4. Gon?alves DA, et al. Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt.Am J PhysiolEndocrinolMetab. 2012 Jan 1;302(1):E123-33.
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