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Org 25543 hydrochloride

CAS No. 495076-64-7

Org 25543 hydrochloride( —— )

Catalog No. M27512 CAS No. 495076-64-7

Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	195	Get Quote
10MG	284	Get Quote
25MG	476	Get Quote
50MG	691	Get Quote
100MG	972	Get Quote
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Biological Information

Product Name

Org 25543 hydrochloride
Note

Research use only, not for human use.
Brief Description

Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells.
Description

Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

GlyT
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

495076-64-7
Formula Weight

448.99
Molecular Formula

C24H33ClN2O4
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCC1)N(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Catalfo A, et al. Rufloxacin induced photosensitization in bio-models of increasing complexity. Photochem Photobiol Sci. 2005 Mar;4(3):304-14.

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