BW 755C

CAS No. 66000-40-6

BW 755C( —— )

Catalog No. M27503 CAS No. 66000-40-6

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 53 Get Quote
10MG 71 Get Quote
25MG 111 Get Quote
50MG 158 Get Quote
100MG 231 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    BW 755C
  • Note
    Research use only, not for human use.
  • Brief Description
    BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
  • Description
    BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.(In Vitro):BW 755C is approximately equipotent inhibitors of COX-1 and COX-2 in intact cells.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Immature Wistar rats ~22 days of age Dosage:0.03, 0.1, 0.3, 1.0, 3.1 and 10 mg/rat Administration:Subcutaneous injection, once Result:Reduced 5-HETE (moderately) and 12-HETE (strongly).
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Lipoxygenase
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    66000-40-6
  • Formula Weight
    229.2
  • Molecular Formula
    C10H10F3N3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (436.30 mM)
  • SMILES
    NC(CC1)=NN1c1cccc(C(F)(F)F)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chao W, et al. Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways. Sci Rep. 2019 Feb 20;9(1):2344.
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