5-LOX-IN-1( —— )

Catalog No. M35529 CAS No. 55040-82-9

5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

5-LOX-IN-1
Note

Research use only, not for human use.
Brief Description

5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
Description

5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation.
In Vitro

5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM.
In Vivo

——
Synonyms

——
Pathway

Immunology/Inflammation
Target

Lipoxygenase
Recptor

Lipoxygenase
Research Area

——
Indication

——

Chemical Information

CAS Number

55040-82-9
Formula Weight

350.43
Molecular Formula

C20H18N2O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (285.36 mM; Ultrasonic (<60°C)
SMILES

O=C(c1sc(nc1-c1ccccc1)N1CCOCC1)c1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Sinha S, et al. Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase. Eur J Med Chem. 2018 Oct 5;158:34-50.?

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