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AZ 11645373

CAS No. 227088-94-0

AZ 11645373( 3-[1-[[(3'-NITRO[1,1'-BIPHENYL]-4-YL)OXY]METHYL]-3-(4-PYRIDINYL)PROPYL]-2,4-THIAZOLIDINEDIONE )

Catalog No. M27445 CAS No. 227088-94-0

AZ 11645373 is a highly selective and potent human P2X7 receptor antagonist that has no effect on mouse/rat P2X7 receptor.

Purity : >98% (HPLC)

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Biological Information

Product Name

AZ 11645373
Note

Research use only, not for human use.
Brief Description

AZ 11645373 is a highly selective and potent human P2X7 receptor antagonist that has no effect on mouse/rat P2X7 receptor.
Description

AZ 11645373 is a highly selective and potent human P2X7 receptor antagonist that has no effect on mouse/rat P2X7 receptor.
In Vitro

——
In Vivo

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Synonyms

3-[1-[[(3'-NITRO[1,1'-BIPHENYL]-4-YL)OXY]METHYL]-3-(4-PYRIDINYL)PROPYL]-2,4-THIAZOLIDINEDIONE
Pathway

Membrane Transporter/Ion Channel
Target

P2X Receptor
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

227088-94-0
Formula Weight

463.51
Molecular Formula

C24H21N3O5S
Purity

>98% (HPLC)
Solubility

——
SMILES

[O-][N+](=O)c1cccc(c1)-c1ccc(OCC(CCc2ccncc2)N2C(=O)CSC2=O)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Qiao-yu Yuan,et al. Chemical Constituents from Cremastra appendiculata. Zhong Yao Cai. 2015 Feb;38(2):298-301.

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