AZ 11645373

CAS No. 227088-94-0

AZ 11645373( 3-[1-[[(3'-NITRO[1,1'-BIPHENYL]-4-YL)OXY]METHYL]-3-(4-PYRIDINYL)PROPYL]-2,4-THIAZOLIDINEDIONE )

Catalog No. M27445 CAS No. 227088-94-0

AZ 11645373 is a highly selective and potent human P2X7 receptor antagonist that has no effect on mouse/rat P2X7 receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 107 In Stock
5MG 103 In Stock
10MG 148 In Stock
25MG 250 In Stock
50MG 346 In Stock
100MG 483 In Stock
200MG 643 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AZ 11645373
  • Note
    Research use only, not for human use.
  • Brief Description
    AZ 11645373 is a highly selective and potent human P2X7 receptor antagonist that has no effect on mouse/rat P2X7 receptor.
  • Description
    AZ 11645373 is a highly selective and potent human P2X7 receptor antagonist that has no effect on mouse/rat P2X7 receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    3-[1-[[(3'-NITRO[1,1'-BIPHENYL]-4-YL)OXY]METHYL]-3-(4-PYRIDINYL)PROPYL]-2,4-THIAZOLIDINEDIONE
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    P2X Receptor
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    227088-94-0
  • Formula Weight
    463.51
  • Molecular Formula
    C24H21N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [O-][N+](=O)c1cccc(c1)-c1ccc(OCC(CCc2ccncc2)N2C(=O)CSC2=O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Qiao-yu Yuan,et al. Chemical Constituents from Cremastra appendiculata. Zhong Yao Cai. 2015 Feb;38(2):298-301.
molnova catalog
related products
  • A 438079

    A 438079 is a potent, and selective antagonist of P2X7 receptor (pIC50: 6.9).

  • Eliapixant

    Eliapixant (BAY 1817080) is a potent and selective antagonist of P2X3 receptor, with an IC50 of 8 nM. Eliapixant can be used for the research of refractory chronic cough.

  • JNJ-42253432

    JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.