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HBX 41108

CAS No. 924296-39-9

HBX 41108( HBX-41108 )

Catalog No. M27424 CAS No. 924296-39-9

HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	80	In Stock
5MG	73	In Stock
10MG	117	In Stock
25MG	235	In Stock
50MG	368	In Stock
100MG	554	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

HBX 41108
Note

Research use only, not for human use.
Brief Description

HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Description

HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
In Vitro

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In Vivo

——
Synonyms

HBX-41108
Pathway

Proteasome/Ubiquitin
Target

DUB
Recptor

Bax|Bcl-2|Caspase-3
Research Area

——
Indication

——

Chemical Information

CAS Number

924296-39-9
Formula Weight

266.64
Molecular Formula

C13H3ClN4O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (937.59 mM)
SMILES

Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhou D, et al. Antiproliferative steroidal glycosides from rhizomes of Polygonatum sibiricum. Phytochemistry. 2019;164:172-183.

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