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Home - Products - Metabolic Enzyme/Protease - P450 - Uniconazole

Uniconazole

CAS No. 83657-22-1

Uniconazole( —— )

Catalog No. M27414 CAS No. 83657-22-1

Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Uniconazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM).
  • Description
    Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis.
  • In Vitro
    ——
  • In Vivo
    Uniconazole (0-50 μM) effectively blocks ABA 8’-hydroxylase activity and enhances drought tolerance in vivo.Uniconazole increases the activities of antioxidant enzymes, promotes accumulation of proline and soluble sugars, and reduces accumulation of malondialdehyde. Animal Model:Arabidopsis Dosage:0.5, 1, 5, 25, 50 μM Administration:Result:Inhibited PA (phaseic acid) production and enhanced drought tolerance.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    β-glucuronidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    83657-22-1
  • Formula Weight
    291.78
  • Molecular Formula
    C15H18ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (342.72 mM)
  • SMILES
    CC(C)(C)C(O)C(=C/c1ccc(Cl)cc1)\n1cncn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Taha M, et al. Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorg Chem. 2016;68:56-63.
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