Estramustine( NSC89201 | LEO275 )

Catalog No. M27308 CAS No. 2998-57-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Estramustine
Note

Research use only, not for human use.
Brief Description

Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.
Description

Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.
In Vitro

——
In Vivo

——
Synonyms

NSC89201 | LEO275
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Microtubule/Tubulin
Recptor

Ephrin Receptor
Research Area

——
Indication

——

CAS Number

2998-57-4
Formula Weight

440.4
Molecular Formula

C23H31Cl2NO3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (227.07 mM)
SMILES

C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(N(CCCl)CCCl)=O)=C4)[C@@]3([H])CC2
Chemical Name

——

1.Wu B, et al. Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol. 2017 Mar 16;24(3):293-305.

Calculator

molnova catalog