Estramustine
CAS No. 2998-57-4
Estramustine( NSC89201 | LEO275 )
Catalog No. M27308 CAS No. 2998-57-4
Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 44 | In Stock |
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| 5MG | 37 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 122 | In Stock |
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| 50MG | 198 | In Stock |
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| 100MG | 323 | In Stock |
|
| 200MG | 476 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEstramustine
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NoteResearch use only, not for human use.
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Brief DescriptionEstramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.
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DescriptionEstramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.
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In Vitro——
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In Vivo——
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SynonymsNSC89201 | LEO275
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorEphrin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2998-57-4
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Formula Weight440.4
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Molecular FormulaC23H31Cl2NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (227.07 mM)
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SMILESC[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(N(CCCl)CCCl)=O)=C4)[C@@]3([H])CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu B, et al. Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol. 2017 Mar 16;24(3):293-305.
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