Estramustine

CAS No. 2998-57-4

Estramustine( NSC89201 | LEO275 )

Catalog No. M27308 CAS No. 2998-57-4

Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 44 In Stock
5MG 37 In Stock
10MG 61 In Stock
25MG 122 In Stock
50MG 198 In Stock
100MG 323 In Stock
200MG 476 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Estramustine
  • Note
    Research use only, not for human use.
  • Brief Description
    Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties.
  • Description
    Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC89201 | LEO275
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Ephrin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2998-57-4
  • Formula Weight
    440.4
  • Molecular Formula
    C23H31Cl2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (227.07 mM)
  • SMILES
    C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(N(CCCl)CCCl)=O)=C4)[C@@]3([H])CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wu B, et al. Potent and Selective EphA4 Agonists for the Treatment of ALS. Cell Chem Biol. 2017 Mar 16;24(3):293-305.
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