Cart
sales@molnova.com
Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - FiVe1

FiVe1

CAS No. 932359-76-7

FiVe1( FiVe1 | FiVe 1 | FiVe-1 )

Catalog No. M16670 CAS No. 932359-76-7

FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 895 In Stock
5MG 758 In Stock
10MG 1036 In Stock
25MG 1568 In Stock
50MG 2074 In Stock
100MG 2725 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    FiVe1
  • Note
    Research use only, not for human use.
  • Brief Description
    FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase.
  • Description
    FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase, causes mitotic catastrophe, multinucleation, and the loss of stemness in cancer cells; selectively and irreversibly inhibits the growth of mesenchymally transformed breast cancer cells ( FOXC2-HMLER cells IC50=234 nM) and soft tissue sarcomas of diverse histological subtypes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FiVe1 | FiVe 1 | FiVe-1
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Microtubule/Tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    932359-76-7
  • Formula Weight
    359.254
  • Molecular Formula
    C18H16Cl2N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC1=CC(N2CCN(C3=C4C=CC=C(Cl)C4=NN=C3)CC2)=CC=C1
  • Chemical Name
    8-chloro-4-(4-(3-chlorophenyl)piperazin-1-yl)cinnoline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bollong MJ, et al. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9903-E9912.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Lys-SMCC-DM1

    DM1 is a tubulin inhibitor.?Lys-SMCC-DM1 is the active metabolite of DM1.?

  • BMS-582949

    BMS-582949 is a potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor with IC50 of 13 nM, inhibiting both p38 kinase activity and activation of p38.

  • Tubulin inhibitor 24

    Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.

Sign In Join Free