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Dehydroabiethylamine
CAS No. 1446-61-3
Dehydroabiethylamine( Leelamine | Leelamine free base | NSC-2955 | NSC 2955 | NSC2955 )
Catalog No. M27157 CAS No. 1446-61-3
Dehydroabiethylamine is an inducer of hepatic CYP2B activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 31 | In Stock |
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Biological Information
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Product NameDehydroabiethylamine
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NoteResearch use only, not for human use.
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Brief DescriptionDehydroabiethylamine is an inducer of hepatic CYP2B activity.
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DescriptionDehydroabiethylamine is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.
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In Vitro——
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In Vivo——
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SynonymsLeelamine | Leelamine free base | NSC-2955 | NSC 2955 | NSC2955
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorNF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number1446-61-3
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Formula Weight285.475
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Molecular FormulaC20H31N
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (350.30 mM)
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SMILESCC(C)c1ccc2c(CC[C@H]3[C@](C)(CN)CCC[C@]23C)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Okolotowicz KJ, et al. Selective benzimidazole inhibitors of the antigen receptor-mediated NF-kappaB activationpathway. Bioorg Med Chem. 2010 Mar 1;18(5):1918-24.
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