Cart
sales@molnova.com
Bis-Tos-PEG4
CAS No. 37860-51-8
Bis-Tos-PEG4( PROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate) )
Catalog No. M27007 CAS No. 37860-51-8
Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 27 | In Stock |
|
Biological Information
-
Product NameBis-Tos-PEG4
-
NoteResearch use only, not for human use.
-
Brief DescriptionBis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
-
DescriptionBis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
SynonymsPROTAC Linker 16 | 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane | Tetraethylene glycol di(p-toluenesulfonate)
-
PathwayOthers
-
TargetOther Targets
-
RecptorBcl-2| Caspase-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number37860-51-8
-
Formula Weight502.59
-
Molecular FormulaC22H30O9S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
A-18-F-NH2 |Morphine...
Neuropeptide AF (cattle), an amidated octadecapeptide, is RFamide neuropeptide. Neuropeptide AF (cattle) acts as a ligand of Mas-related gene receptor A4 (MrgprA4) (Mas-related G-protein-coupled Receptor (MRGPR)) (EC50 of ~60 nM) and MrgprC11 (EC50 of ~300 nM). Neuropeptide AF (cattle) also activate to the G protein-coupled receptors NPFF1 (Neuropeptide Y Receptor) (EC50 of ~25-325 nM) and NPFF2 (EC50 of ~1-5 nM). Neuropeptide AF (cattle) shows anti-opiate and related pain modulation effects.
-
N3-C4-NHS ester
N3-C4-NHS ester is a non cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
-
Ethylmalonic acid
Ethylmalonic acid can be found in blood cerebrospinal fluid (CSF) and urine as well as in human fibroblasts prostate and skeletal muscle tissues. Moreover ethylmalonic acid is found to be associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency. Ethylmalonic acid is a non-carcinogenic potentially toxic compound.
