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Hydroxy-PEG10-acid
CAS No. 2375611-66-6
Hydroxy-PEG10-acid( HO-PEG10-CH2CH2COOH )
Catalog No. M26966 CAS No. 2375611-66-6
Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 29 | In Stock |
|
| 50MG | 38 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameHydroxy-PEG10-acid
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NoteResearch use only, not for human use.
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Brief DescriptionHydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
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DescriptionHydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsHO-PEG10-CH2CH2COOH
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PathwayOthers
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TargetOther Targets
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RecptorPIP5K1α
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Research Area——
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Indication——
Chemical Information
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CAS Number2375611-66-6
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Formula Weight530.608
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Molecular FormulaC23H46O13
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Purity>98% (HPLC)
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Solubility——
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SMILESOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sarwar M, et al. Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes MDV3100 resistance in prostate cancer cells. Oncotarget. 2016 Sep 27;7(39):63065-63081.
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