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Biotin-PEG2-C2-iodoacetamide

CAS No. 292843-75-5

Biotin-PEG2-C2-iodoacetamide( Biotin-PEG2-C2-iodoacetamide | Biotin-PEG2-iodoacetamide )

Catalog No. M26903 CAS No. 292843-75-5

Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Biotin-PEG2-C2-iodoacetamide
  • Note
    Research use only, not for human use.
  • Brief Description
    Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Biotin-PEG2-C2-iodoacetamide | Biotin-PEG2-iodoacetamide
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    SARS-CoV| SARS-CoV 3CLpro
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    292843-75-5
  • Formula Weight
    542.43
  • Molecular Formula
    C18H31IN4O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCNC(=O)CI)[C@@]1([H])NC(=O)N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ghosh AK, et, al. Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5684-8.
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