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Biotin-PEG2-C2-iodoacetamide
CAS No. 292843-75-5
Biotin-PEG2-C2-iodoacetamide( Biotin-PEG2-C2-iodoacetamide | Biotin-PEG2-iodoacetamide )
Catalog No. M26903 CAS No. 292843-75-5
Biotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 36 | In Stock |
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| 10MG | 51 | In Stock |
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| 25MG | 86 | In Stock |
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| 50MG | 138 | In Stock |
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| 100MG | 221 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBiotin-PEG2-C2-iodoacetamide
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NoteResearch use only, not for human use.
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Brief DescriptionBiotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionBiotin-PEG2-C2-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsBiotin-PEG2-C2-iodoacetamide | Biotin-PEG2-iodoacetamide
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PathwayOthers
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TargetOther Targets
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RecptorSARS-CoV| SARS-CoV 3CLpro
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Research Area——
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Indication——
Chemical Information
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CAS Number292843-75-5
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Formula Weight542.43
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Molecular FormulaC18H31IN4O5S
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCNC(=O)CI)[C@@]1([H])NC(=O)N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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α-ANF(1-28), human
Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC50 of 1.2 nM.
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GPX4-IN-5
GPX4-IN-5 is a small molecule covalent GPX4 inhibitor (IC50: 0.12 μM) with antitumour activity.
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ND-646
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)ND-646-an allosteric inhibitor of the ACC enzymes. ACC1 and ACC2 that prevents ACC subunit dimerization-to suppress fatty acid synthesis in vitro and in vivo.?
