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SS-208

CAS No. 2245942-72-5

SS-208( SS208 )

Catalog No. M26826 CAS No. 2245942-72-5

SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 112 In Stock
10MG 179 In Stock
25MG 312 In Stock
50MG 439 In Stock
100MG 603 In Stock
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Biological Information

  • Product Name
    SS-208
  • Note
    Research use only, not for human use.
  • Brief Description
    SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
  • Description
    SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.(In Vivo):In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth.
  • In Vitro
    ——
  • In Vivo
    SS-208 (25 mg/kg, ip) significantly reduces the tumor growth in melanoma murine model. Animal Model:C57BL/6 mice injected immunogenic murine SM1 melanoma cells subcutaneously.Dosage:25 mg/kg.Administration:IP on day 4, 7, 12, 15 and 18.Result:Significantly reduced the tumor growth.
  • Synonyms
    SS208
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    5-HT2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2245942-72-5
  • Formula Weight
    344.15
  • Molecular Formula
    C13H11Cl2N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (363.21 mM)
  • SMILES
    ONC(=O)c1cc(CCNC(=O)c2ccc(Cl)c(Cl)c2)on1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gonyou HW, et al. Effects of amperozide and azaperone on aggression and productivity of growing-finishing pigs. J Anim Sci. 1988 Nov;66(11):2856-64.
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