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MC-1568
CAS No. 852475-26-4
MC-1568( MC1568 )
Catalog No. M16194 CAS No. 852475-26-4
A potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 5MG | 30 | In Stock |
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| 10MG | 49 | In Stock |
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| 25MG | 89 | In Stock |
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| 50MG | 135 | In Stock |
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| 100MG | 244 | In Stock |
|
| 200MG | 423 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMC-1568
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A.
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DescriptionA potent and selective class IIa HDAC inhibitor with IC50 of 220 nM for maize HD1-A; displays 176-fold selectivity over HD1-B; increases the accumulation of acetylated H3 and H4 histones in MCF-7 cells at 20 uM; promotes neurite growth and arbourisation and protects neurite arbours against neurotoxic insult.
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In Vitro——
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In Vivo——
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SynonymsMC1568
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHD1-A(Maize)|HD1-B(Maize)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number852475-26-4
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Formula Weight314.311
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Molecular FormulaC17H15FN2O3
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Purity>98% (HPLC)
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SolubilityDMSO: 18.5 mg/mL
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SMILESO=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C
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Chemical Name2-Propenamide, 3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-, (2E)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mai A, et al. J Med Chem. 2005 May 5;48(9):3344-53.
2. Duong V, et al. Mol Cancer Res. 2008 Dec;6(12):1908-19.
3. Collins LM, et al. Mol Neurobiol. 2015;51(3):1432-42.
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