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AZ10606120 dihydrochloride
CAS No. 607378-18-7
AZ10606120 dihydrochloride( —— )
Catalog No. M26620 CAS No. 607378-18-7
AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 154 | Get Quote |
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| 5MG | 141 | Get Quote |
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| 10MG | 227 | Get Quote |
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| 25MG | 454 | Get Quote |
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| 50MG | 640 | Get Quote |
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| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAZ10606120 dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionAZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.
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DescriptionAZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth. AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM and it is little or no effect at other P2XR subtypes.
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In Vitro——
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In VivoAnimal Model:LPS-induced anhedonia miceDosage:2 mg/kg Administration:i.p., pretreated at 30 min before LPS injection Result:Restored the decline in sucrose consumption, indicated by an sucrose preference test (SPT).
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetP2X Receptor
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number607378-18-7
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Formula Weight495.49
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Molecular FormulaC25H36Cl2N4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 8.33 mg/mL (16.81 mM)
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SMILESCl.Cl.OCCNCCNc1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chung HK, et al. Plasma phospholipid arachidonic acid and lignoceric acid are associated with the risk of cardioembolic stroke. Nutr Res. 2015 Nov;35(11):1001-8.
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