Cart
sales@molnova.com
Zandelisib
CAS No. 1401436-95-0
Zandelisib( ME-401 | PWT-143 )
Catalog No. M26519 CAS No. 1401436-95-0
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 225 | In Stock |
|
| 5MG | 178 | In Stock |
|
| 10MG | 278 | In Stock |
|
| 25MG | 487 | In Stock |
|
| 50MG | 641 | In Stock |
|
| 100MG | 882 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameZandelisib
-
NoteResearch use only, not for human use.
-
Brief DescriptionZandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
-
DescriptionZandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.(In Vitro):Zandelisib inhibits PI3Ks(p110α, p110β, p110γ and p110δ with IC50s of 4, 976 nM, 605 nM, 817 nM and 3.5 nM, respectivey).
-
In Vitro——
-
In Vivo——
-
SynonymsME-401 | PWT-143
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1401436-95-0
-
Formula Weight576.697
-
Molecular FormulaC31H38F2N8O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 33.33 mg/mL (57.80 mM)
-
SMILESCN1CCC(CC1)c1ccccc1CC(C)(C)Nc1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Llado V, et al. Minerval induces apoptosis in Jurkat and other cancer cells. J Cell Mol Med. 2010 Mar;14(3):659-70.
molnova catalog
related products
-
Dactolisib Tosylate
Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor targeting PI3K and mTOR, with IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. It also inhibits mTORC1 and mTORC2.
-
CL27c
CL27c is a cell-permeable, inhaled lipophilic ester prodrug of CL27e, which is a potent, selective pan-class I PI3K inhibitor, CL27c is inactive in PI3K enzymatic assay.
-
Palosuran hydrochlor...
Palosuran is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6±0.2 nM.
