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SMS1-IN-1

CAS No. 1807943-38-9

SMS1-IN-1( —— )

Catalog No. M26452 CAS No. 1807943-38-9

SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 186 In Stock
5MG 155 In Stock
10MG 217 In Stock
25MG 353 In Stock
50MG 547 In Stock
100MG 807 In Stock
200MG 1088 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    SMS1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.
  • Description
    SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies. (In Vitro):SMS1-IN-1 (2.5, 10 and 50 μM) shows inhibitory effect against SMS1 in a dose-dependent manner.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    D2 receptor| D3 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1807943-38-9
  • Formula Weight
    503.41
  • Molecular Formula
    C23H23BrN2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (496.61 mM)
  • SMILES
    Brc1ccc(CNC(=O)COc2ccc(cc2)S(=O)(=O)NCCc2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Holmes et al (2010) The identification of a selective DA D2 partial agonist, D3 antagonist displaying high levels of brain exposure. Bioorg.Med.Chem.Lett. 20 2013
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