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MHI-148
CAS No. 172971-76-5
MHI-148( —— )
Catalog No. M36944 CAS No. 172971-76-5
MHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 33 | In Stock |
|
| 50MG | 56 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMHI-148
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NoteResearch use only, not for human use.
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Brief DescriptionMHI-148 is a tumor-targeting near-infrared heptamethylenecarbocyanine dye for the detection, diagnosis, and study of cancer.
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DescriptionMHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells.
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In VitroMHI-148 (10 μM, 1 h)?is significantly more absorbed in HT-29 colon carcinoma cells than in normal NIH3T3 fibroblasts and has tumor imaging and targeting properties. MHI-148 (0-1.5 μM, 3 days) causes only negligible toxicity in HT-29 and NIH3T3 cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number172971-76-5
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Formula Weight764.23
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Molecular FormulaC42H52BrClN2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20.83 mg/mL (27.26 mM; Ultrasonic )
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SMILES[Br-].O=C(O)CCCCCN1C=2C=CC=CC2C(C1=CC=C3C(Cl)=C(C=CC4=[N+](C=5C=CC=CC5C4(C)C)CCCCCC(=O)O)CCC3)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Athira Raveendran, et al. Heptamethine Cyanine Dye MHI-148-Mediated Drug Delivery System to Enhance the Anticancer Efficiency of Paclitaxel. Int J Nanomedicine. 2021 Oct 21;16:7169-7180.?
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