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SHIP2-IN-1
CAS No. 2252247-80-4
SHIP2-IN-1( —— )
Catalog No. M26440 CAS No. 2252247-80-4
SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 181 | In Stock |
|
| 5MG | 164 | In Stock |
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| 10MG | 259 | In Stock |
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| 25MG | 429 | In Stock |
|
| 50MG | 591 | In Stock |
|
| 100MG | 798 | In Stock |
|
| 200MG | 1070 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSHIP2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionSHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
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DescriptionSHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.(In Vitro):PI(3,4)P2 production in HT22 cellssignificantly inhibited by SHIP2-IN-1 (10 μM) .
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In VitroSHIP2-IN-1 (Compound 43; 10 μM) significantly inhibits PI(3,4)P2 production in HT22 cells.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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Recptorα4β1δ GABAA receptor| α4β3δ GABAA receptor| αβγ GABAA receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2252247-80-4
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Formula Weight379.22
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Molecular FormulaC17H13Cl2FN4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (263.70 mM)
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SMILESC[C@@H](Oc1cncc(c1)-c1cnc(N)nc1)c1c(Cl)ccc(F)c1Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SC-43
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.SC-43, a sorafenib derivative.
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Xanthotoxol
Xanthotoxol exhibits dose-graded sedative activity in dogs, cats, rats, mice and hamsters. Xanthotoxol at concentrations of 5 to 5 micrograms/ml inhibits the growth of cells, decreases amount of cell protein, mitotic index.
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JMS-053
JMS-053 is a potent and selective inhibitor of the phosphatase DUSP3, inhibits PTP4A3, PTP4A1, PTP4A2 and CDC25B, inhibits cancer cell migration and sphere growth, and avoids disruption of the microvascular endothelial barrier by vascular endothelial growth factor or lipopolysaccharide.
