SHIP2-IN-1( —— )

Catalog No. M26440 CAS No. 2252247-80-4

SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	181	In Stock
5MG	164	In Stock
10MG	259	In Stock
25MG	429	In Stock
50MG	591	In Stock
100MG	798	In Stock
200MG	1070	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SHIP2-IN-1
Note

Research use only, not for human use.
Brief Description

SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
Description

SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.(In Vitro):PI(3,4)P2 production in HT22 cellssignificantly inhibited by SHIP2-IN-1 (10 μM) .
In Vitro

SHIP2-IN-1 (Compound 43; 10 μM) significantly inhibits PI(3,4)P2 production in HT22 cells.
In Vivo

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Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Phosphatase
Recptor

α4β1δ GABAA receptor| α4β3δ GABAA receptor| αβγ GABAA receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

2252247-80-4
Formula Weight

379.22
Molecular Formula

C17H13Cl2FN4O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (263.70 mM)
SMILES

C[C@@H](Oc1cncc(c1)-c1cnc(N)nc1)c1c(Cl)ccc(F)c1Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Hoestgaard-Jensen K, et al. Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain. J Neurosci. 2014 Dec 3;34(49):16256-72.

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