Cart
sales@molnova.com
SHIP2-IN-1
CAS No. 2252247-80-4
SHIP2-IN-1( —— )
Catalog No. M26440 CAS No. 2252247-80-4
SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 181 | In Stock |
|
| 5MG | 164 | In Stock |
|
| 10MG | 259 | In Stock |
|
| 25MG | 429 | In Stock |
|
| 50MG | 591 | In Stock |
|
| 100MG | 798 | In Stock |
|
| 200MG | 1070 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSHIP2-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionSHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.
-
DescriptionSHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.(In Vitro):PI(3,4)P2 production in HT22 cellssignificantly inhibited by SHIP2-IN-1 (10 μM) .
-
In VitroSHIP2-IN-1 (Compound 43; 10 μM) significantly inhibits PI(3,4)P2 production in HT22 cells.
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetPhosphatase
-
Recptorα4β1δ GABAA receptor| α4β3δ GABAA receptor| αβγ GABAA receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2252247-80-4
-
Formula Weight379.22
-
Molecular FormulaC17H13Cl2FN4O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (263.70 mM)
-
SMILESC[C@@H](Oc1cncc(c1)-c1cnc(N)nc1)c1c(Cl)ccc(F)c1Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hoestgaard-Jensen K, et al. Probing α4βδ GABAA receptor heterogeneity: differential regional effects of a functionally selective α4β1δ/α4β3δ receptor agonist on tonic and phasic inhibition in rat brain. J Neurosci. 2014 Dec 3;34(49):16256-72.
molnova catalog
related products
-
Talabostat mesylate
Talabostat mesylate is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein.
-
Desfesoterodine
5-hydroxymethyl tolterodine (PNU 200577) is a new muscarinic receptor antagonist with Kb of 0.84 nM.
-
TCS 401
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 μM).
