PNZ5( —— )

Catalog No. M26388 CAS No. 1629277-36-6

PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	253	In Stock
5MG	256	In Stock
10MG	375	In Stock
25MG	562	In Stock
50MG	775	In Stock
100MG	1042	In Stock
200MG	1414	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PNZ5
Note

Research use only, not for human use.
Brief Description

PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1.
Description

PNZ5 is a potent and isoxazole-based pan-BET inhibitor, with high selectivity and potency similar to the well-established (+)-JQ1, with a KD of 5.43 nM for BRD4.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

Epigenetic Reader Domain
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

1629277-36-6
Formula Weight

318.376
Molecular Formula

C20H18N2O2
Purity

>98% (HPLC)
Solubility

——
SMILES

[H][C@]1(N(C)C(=O)c2ccc(cc12)-c1c(C)noc1C)c1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ye, C., Jin, M., Jin, C. et al. Inhibitory Effects of Chemical Constituents from Actinidia kolomikta on LPS-Induced Inflammatory Responses. Rev. Bras. Farmacogn. 30, 127–131 (2020).

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