Mocravimod hydrochloride

CAS No. 509088-69-1

Mocravimod hydrochloride( KRP-203 )

Catalog No. M26300 CAS No. 509088-69-1

Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 173 In Stock
5MG 163 In Stock
10MG 264 In Stock
25MG 535 In Stock
50MG 811 In Stock
100MG 1088 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Mocravimod hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).
  • Description
    Mocravimod hydrochloride is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1). (In Vivo):In mHC-disparate rat heart allografts, Mocravimod hydrochloride(orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection. Mocravimod hydrochloride ameliorates atherosclerosis in LDL-R(-/-) Mice.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Inbred male DA (MHC haplotype: RT1a) rats Dosage:0.1 and 1 mg/kg Administration:Orally; daily; for 100 days.Result:Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts.
  • Synonyms
    KRP-203
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    gluconeogenesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    509088-69-1
  • Formula Weight
    480.44
  • Molecular Formula
    C24H27Cl2NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 200 mg/mL (416.28 mM)
  • SMILES
    Cl.NC(CO)(CO)CCc1ccc(Sc2cccc(OCc3ccccc3)c2)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Murray AF, et, al. Phenylpropanoid Glycerol Glucosides Attenuate Glucose Production in Hepatocytes. ACS Omega. 2019 Jun 19;4(6):10670-10676.
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