Hexyl gallate

CAS No. 1087-26-9

Hexyl gallate( Hexyl 3,4,5-trihydroxybenzoate | Gallic acid hexyl ester )

Catalog No. M26248 CAS No. 1087-26-9

Hexyl gallate, an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Hexyl gallate
  • Note
    Research use only, not for human use.
  • Brief Description
    Hexyl gallate, an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).
  • Description
    Hexyl gallate, an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).(In Vitro):Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) inhibits only Rhl-dependent production of rhamnolipid and pyocyanin by inhibiting RhlR, without affecting elastase production and biofilm formation which are regulated by the Las system.Hexyl gallates inhibits pigment production at 10-30 μM, but also exhibited antibacterial activity. Hexyl gallates also exhibits antibacterial activity against CV026 cells. Hexyl gallates inhibits only N-butanoyl homoserine lactone (BHL) production at 100 and 300 μM without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1 H) quinolone (PQS) production.Hexyl gallates, an antimicrobial alternative to copper compounds, inhibits Xanthomonas citri growth in a dose-response manner, showing a more pronounced activity at the range of 30-50 μg/ml, and it targets the membrane of X. citri.
  • In Vitro
    Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) inhibits only Rhl-dependent production of rhamnolipid and pyocyanin by inhibiting RhlR, without affecting elastase production and biofilm formation which are regulated by the Las system.Hexyl gallates inhibits pigment production at 10-30?μM, but also exhibited antibacterial activity. Hexyl gallates also exhibits antibacterial activity against CV026 cells. Hexyl gallates inhibits only N-butanoyl homoserine lactone (BHL) production at 100 and 300?μM without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1?H) quinolone (PQS) production.Hexyl gallates, an antimicrobial alternative to copper compounds, inhibits Xanthomonas citri growth in a dose-response manner, showing a more pronounced activity at the range of 30-50 μg/ml, and it targets the membrane of X. citri.
  • In Vivo
    ——
  • Synonyms
    Hexyl 3,4,5-trihydroxybenzoate | Gallic acid hexyl ester
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    PEGs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1087-26-9
  • Formula Weight
    254.282
  • Molecular Formula
    C13H18O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 41.67 mg/mL (163.87 mM)
  • SMILES
    CCCCCCOC(=O)c1cc(O)c(O)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.
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