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LolCDE-IN-1
CAS No. 1639933-78-0
LolCDE-IN-1( —— )
Catalog No. M21571 CAS No. 1639933-78-0
LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex with antibacterial activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 260 | Get Quote |
|
| 10MG | 410 | Get Quote |
|
| 25MG | 678 | Get Quote |
|
| 50MG | 954 | Get Quote |
|
| 100MG | 1287 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLolCDE-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionLolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex with antibacterial activity.
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DescriptionLolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex with antibacterial activity.
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In VitroLolCDE-IN-1 (compound 2) inhibits the function of the LolCDE complex, which is required for transport of lipoproteins to the outer membrane.LolCDE-IN-1 inhibits E. coli ATCC 25922 and E. coli ATCC 25922 ΔtolCwith MIC with 8 μg/ml and 0.125 μg/ml.LolCDE-IN-1 inhibits bacterial growth by targeting LolCDE to block lipoprotein transport to the outer membrane.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorBacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number1639933-78-0
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Formula Weight345.37
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Molecular FormulaC21H16FN3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 41.67 mg/mL (120.65 mM)
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SMILESFc1ccc(COc2cccc(c2)-c2n[nH]cc2-c2ccncc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nayar AS et al. Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assay. J Bacteriol. 2015 May;197(10):1726-34.
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