Dianemycin

Research use only, not for human use.

Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria.

Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria. Nanchangmycin is a broad spectrum antiviral active against Zika virus

Dianemycin (Nanchangmycin) can be used as a growth promotant in poultry and to cure coccidiosis in chickens. Dianemycin is active against drug resistant strains of malaria. Dianemycin (Nanchangmycin) as a potent inhibitor of Zika virus (ZIKV) entry across all cell types tested including physiologically relevant primary cells. Dianemycin potently reduces infection of all three strains of ZIKV across all three cell types. The IC50s for infection are between 0.1 and 0.4 μM while Dianemycin has low toxicity in these ranges. In addition, DENV is inhibited by Dianemycin across cell types.

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Nanchangmycin (free acid)

GPCR/G Protein

Antibacterial

Bacterial

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35865-33-9

867.11

C47H78O14

>98% (HPLC)

DMSO:150 mg/ml(172.99 mM; Need ultrasonic)

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(-20℃)

With Ice Pack

≥ 2 years