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Home - Products - Metabolic Enzyme/Protease - P450 - ε-?Viniferin

ε-?Viniferin

CAS No. 62218-08-0

ε-?Viniferin( epsilon-Viniferin )

Catalog No. M26204 CAS No. 62218-08-0

ε-Viniferin a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    ε-?Viniferin
  • Note
    Research use only, not for human use.
  • Brief Description
    ε-Viniferin a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.
  • Description
    ε-Viniferin a dimer of resveratrol, shows the inhibitory effects of epsilon-viniferin on human CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2E1, CYP3A4 and CYP4A activities.
  • In Vitro
    Western Blot Analysis Cell Line:A549 cells Concentration:10 μM Incubation Time:1 h Result:Inhibited TGF-β1-induced MMP2, vimentin, Zeb1, p-SMAD2, p-SMAD3, and ABCG2 expression.
  • In Vivo
    Animal Model:A549 cell xenograft nude mice model Dosage:5 mg/kg Administration:i.p., 5 days per week for 4 weeks Result:Inhibited tumor weight and volume.Induced apoptosis in tumor sections.Decreased serum ALT, AST, bilirubin, and creatinine levels.
  • Synonyms
    epsilon-Viniferin
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    62218-08-0
  • Formula Weight
    454.478
  • Molecular Formula
    C28H22O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Oc1ccc(\C=C\c2cc(O)cc3O[C@H]([C@@H](c23)c2cc(O)cc(O)c2)c2ccc(O)cc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Karakurt A, Ozalp M, I?ik S, Stables JP, Dalkara S. Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives. Bioorg Med Chem. 2010 Apr 15;18(8):2902-11.
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